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  3. Isotope-Labeled Compounds NO Synthase Endogenous Metabolite
  4. L-Arginine-13C6 hydrochloride

L-Arginine-13C6 hydrochloride  (Synonyms: (S)-(+)-Arginine-13C6 hydrochloride)

Cat. No.: HY-N0455AS6 Purity: 99.00%
COA Handling Instructions

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L-Arginine-13C6 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

For research use only. We do not sell to patients.

L-Arginine-<sup>13</sup>C<sub>6</sub> hydrochloride Chemical Structure

L-Arginine-13C6 hydrochloride Chemical Structure

CAS No. : 201740-91-2

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1 mg USD 120 In-stock
5 mg USD 360 In-stock
10 mg USD 600 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Arginine-13C6 hydrochloride:

L-Arginine-13C6 hydrochloride Related Antibodies

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Description

L-Arginine-13C6 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Arginine-13C6 hydrochloride Related Antibodies
Molecular Weight

216.62

Formula

13C6H15ClN4O2
CAS No.
Unlabeled CAS

1119-34-2
Appearance

Solid

Color

White to off-white

SMILES

N=[13C](N)N[13CH2][13CH2][13CH2][13C@H](N)[13C](O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1154.09 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6164 mL 23.0819 mL 46.1638 mL
5 mM 0.9233 mL 4.6164 mL 9.2328 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.00%

COA (243 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.6164 mL 23.0819 mL 46.1638 mL 115.4095 mL
5 mM 0.9233 mL 4.6164 mL 9.2328 mL 23.0819 mL
10 mM 0.4616 mL 2.3082 mL 4.6164 mL 11.5409 mL
15 mM 0.3078 mL 1.5388 mL 3.0776 mL 7.6940 mL
20 mM 0.2308 mL 1.1541 mL 2.3082 mL 5.7705 mL
25 mM 0.1847 mL 0.9233 mL 1.8466 mL 4.6164 mL
30 mM 0.1539 mL 0.7694 mL 1.5388 mL 3.8470 mL
40 mM 0.1154 mL 0.5770 mL 1.1541 mL 2.8852 mL
50 mM 0.0923 mL 0.4616 mL 0.9233 mL 2.3082 mL
60 mM 0.0769 mL 0.3847 mL 0.7694 mL 1.9235 mL
80 mM 0.0577 mL 0.2885 mL 0.5770 mL 1.4426 mL
100 mM 0.0462 mL 0.2308 mL 0.4616 mL 1.1541 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Arginine-13C6 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Arginine-13C6201740-91-2(S)-(+)-Arginine-13C6Isotope-Labeled CompoundsNO SynthaseEndogenous MetaboliteNitric oxide synthasesNOSInhibitorinhibitorinhibit

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