2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. NO Synthase Endogenous Metabolite
  4. L-Arginine-d7 hydrochloride

L-Arginine-d7 hydrochloride  (Synonyms: (S)-(+)-Arginine-d7 hydrochloride)

Cat. No.: HY-N0455AS2 Purity: 99.72%
SDS COA Handling Instructions

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L-Arginine-d7 (hydrochloride) is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

For research use only. We do not sell to patients.

L-Arginine-d<sub>7</sub> hydrochloride Chemical Structure

L-Arginine-d7 hydrochloride Chemical Structure

CAS No. : 204244-77-9

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1 mg USD 220 In-stock
5 mg USD 470 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Arginine-d7 hydrochloride:

L-Arginine-d7 hydrochloride Related Antibodies

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Description

L-Arginine-d7 (hydrochloride) is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Arginine-d7 hydrochloride Related Antibodies
Molecular Weight

217.71

Formula

C6H8D7ClN4O2
CAS No.
Unlabeled CAS

1119-34-2
Appearance

Solid

Color

Off-white to light yellow

SMILES

N=C(N)NC([2H])([2H])C([2H])([2H])C([2H])([2H])[C@@](N)([2H])C(O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1148.32 mM; Need ultrasonic)

H2O : 250 mg/mL (1148.32 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5933 mL 22.9663 mL 45.9327 mL
5 mM 0.9187 mL 4.5933 mL 9.1865 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.72%

SDS (393 KB)

COA (247 KB) LCMS (91 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 4.5933 mL 22.9663 mL 45.9327 mL 114.8317 mL
5 mM 0.9187 mL 4.5933 mL 9.1865 mL 22.9663 mL
10 mM 0.4593 mL 2.2966 mL 4.5933 mL 11.4832 mL
15 mM 0.3062 mL 1.5311 mL 3.0622 mL 7.6554 mL
20 mM 0.2297 mL 1.1483 mL 2.2966 mL 5.7416 mL
25 mM 0.1837 mL 0.9187 mL 1.8373 mL 4.5933 mL
30 mM 0.1531 mL 0.7655 mL 1.5311 mL 3.8277 mL
40 mM 0.1148 mL 0.5742 mL 1.1483 mL 2.8708 mL
50 mM 0.0919 mL 0.4593 mL 0.9187 mL 2.2966 mL
60 mM 0.0766 mL 0.3828 mL 0.7655 mL 1.9139 mL
80 mM 0.0574 mL 0.2871 mL 0.5742 mL 1.4354 mL
100 mM 0.0459 mL 0.2297 mL 0.4593 mL 1.1483 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Arginine-d7 hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Arginine-d7204244-77-9(S)-(+)-Arginine-d7NO SynthaseEndogenous MetaboliteNitric oxide synthasesNOSInhibitorinhibitorinhibit

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