L-Asparagine-d₃ hydrate

Name: L-Asparagine-d 3 hydrate
Brand: MedChemExpress
SKU: HY-N0667S5
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0667S5 Purity: 99.64%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Asparagine-d₃ (hydrate) is the deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

For research use only. We do not sell to patients.

L-Asparagine-d<sub>3</sub> hydrate Chemical Structure

L-Asparagine-d₃ hydrate Chemical Structure

CAS No. : 2483831-59-8

Size	Price	Stock	Quantity
1 mg	USD 115	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Asparagine-d₃ hydrate:

L-Asparagine In-stock

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References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

153.15

Formula

C₄H₇D₃N₂O₄

CAS No.

2483831-59-8

Unlabeled CAS

70-47-3

Appearance

Solid

Color

White to off-white

SMILES

NC(C([2H])([2H])[C@@](N)([2H])C(O)=O)=O.[H]O[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 6.67 mg/mL (43.55 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.5295 mL	32.6477 mL	65.2955 mL
5 mM	1.3059 mL	6.5295 mL	13.0591 mL
10 mM	0.6530 mL	3.2648 mL	6.5295 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.64%

Select Batch:

Data Sheet (273 KB) SDS (251 KB)

COA (252 KB) Elemental Analysis Report (111 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O	1 mM	6.5295 mL	32.6477 mL	65.2955 mL	163.2387 mL
	5 mM	1.3059 mL	6.5295 mL	13.0591 mL	32.6477 mL
	10 mM	0.6530 mL	3.2648 mL	6.5295 mL	16.3239 mL
	15 mM	0.4353 mL	2.1765 mL	4.3530 mL	10.8826 mL
	20 mM	0.3265 mL	1.6324 mL	3.2648 mL	8.1619 mL
	25 mM	0.2612 mL	1.3059 mL	2.6118 mL	6.5295 mL
	30 mM	0.2177 mL	1.0883 mL	2.1765 mL	5.4413 mL
	40 mM	0.1632 mL	0.8162 mL	1.6324 mL	4.0810 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.