L-Aspartic acid-¹⁵N

Name: L-Aspartic acid- 15 N
Brand: MedChemExpress
SKU: HY-N0666S3
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0666S3 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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L-Aspartic acid-¹⁵N is the ¹⁵N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[1].

For research use only. We do not sell to patients.

L-Aspartic acid-<sup>15</sup>N Chemical Structure

L-Aspartic acid-¹⁵N Chemical Structure

CAS No. : 3715-16-0

Size	Price	Stock	Quantity
5 mg	USD 38	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Aspartic acid-¹⁵N:

L-Aspartic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

L-Aspartic acid-¹⁵N is the ¹⁵N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

134.10

Formula

C₄H₇¹⁵NO₄

CAS No.

3715-16-0

Unlabeled CAS

56-84-8

Appearance

Solid

Color

White to off-white

SMILES

OC(C[C@H]([15NH2])C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

1M NaOH : 100 mg/mL (745.71 mM; ultrasonic and adjust pH to 12 with NaOH)

1 M NaOH : 100 mg/mL (745.71 mM; ultrasonic and adjust pH to 12 with NaOH)

H₂O : 2 mg/mL (14.91 mM; ultrasonic and warming and heat to 60°C)

DMSO : 1 mg/mL (7.46 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.4571 mL	37.2856 mL	74.5712 mL
5 mM	1.4914 mL	7.4571 mL	14.9142 mL
10 mM	0.7457 mL	3.7286 mL	7.4571 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (247 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406. [Content Brief]

[3]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O / H₂O / 1M NaOH / 1 M NaOH	1 mM	7.4571 mL	37.2856 mL	74.5712 mL	186.4280 mL
DMSO / H₂O / H₂O / 1M NaOH / 1 M NaOH	5 mM	1.4914 mL	7.4571 mL	14.9142 mL	37.2856 mL
H₂O / H₂O / 1M NaOH / 1 M NaOH	10 mM	0.7457 mL	3.7286 mL	7.4571 mL	18.6428 mL
1M NaOH / 1 M NaOH	15 mM	0.4971 mL	2.4857 mL	4.9714 mL	12.4285 mL
	20 mM	0.3729 mL	1.8643 mL	3.7286 mL	9.3214 mL
	25 mM	0.2983 mL	1.4914 mL	2.9828 mL	7.4571 mL
	30 mM	0.2486 mL	1.2429 mL	2.4857 mL	6.2143 mL
	40 mM	0.1864 mL	0.9321 mL	1.8643 mL	4.6607 mL
	50 mM	0.1491 mL	0.7457 mL	1.4914 mL	3.7286 mL
	60 mM	0.1243 mL	0.6214 mL	1.2429 mL	3.1071 mL
	80 mM	0.0932 mL	0.4661 mL	0.9321 mL	2.3304 mL
	100 mM	0.0746 mL	0.3729 mL	0.7457 mL	1.8643 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.