2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. L-Citrulline-d4

L-Citrulline-d4 is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

For research use only. We do not sell to patients.

L-Citrulline-d<sub>4</sub> Chemical Structure

L-Citrulline-d4 Chemical Structure

CAS No. : 1217474-00-4

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Citrulline-d4:

L-Citrulline-d4 Related Antibodies

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  • Purity & Documentation

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Description

L-Citrulline-d4 is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Citrulline-d4 Related Antibodies
Molecular Weight

179.21

Formula

C6H9D4N3O3
CAS No.
Unlabeled CAS

372-75-8
Appearance

Solid

Color

White to off-white

SMILES

NC(NC([2H])([2H])C([2H])([2H])C[C@H](N)C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (279.00 mM)

H2O : 50 mg/mL (279.00 mM; Need ultrasonic and warming)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5800 mL 27.9002 mL 55.8005 mL
5 mM 1.1160 mL 5.5800 mL 11.1601 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 5.5800 mL 27.9002 mL 55.8005 mL 139.5011 mL
5 mM 1.1160 mL 5.5800 mL 11.1601 mL 27.9002 mL
10 mM 0.5580 mL 2.7900 mL 5.5800 mL 13.9501 mL
15 mM 0.3720 mL 1.8600 mL 3.7200 mL 9.3001 mL
20 mM 0.2790 mL 1.3950 mL 2.7900 mL 6.9751 mL
25 mM 0.2232 mL 1.1160 mL 2.2320 mL 5.5800 mL
30 mM 0.1860 mL 0.9300 mL 1.8600 mL 4.6500 mL
40 mM 0.1395 mL 0.6975 mL 1.3950 mL 3.4875 mL
50 mM 0.1116 mL 0.5580 mL 1.1160 mL 2.7900 mL
60 mM 0.0930 mL 0.4650 mL 0.9300 mL 2.3250 mL
80 mM 0.0698 mL 0.3488 mL 0.6975 mL 1.7438 mL
100 mM 0.0558 mL 0.2790 mL 0.5580 mL 1.3950 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Citrulline-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Citrulline-d41217474-00-4Endogenous MetaboliteInhibitorinhibitorinhibit

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