L-Citrulline-d₇

Name: L-Citrulline-d 7
Brand: MedChemExpress
SKU: HY-N0391S5
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0391S5 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Citrulline-d₇ is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

For research use only. We do not sell to patients.

L-Citrulline-d<sub>7</sub> Chemical Structure

L-Citrulline-d₇ Chemical Structure

CAS No. : 2483831-24-7

Size	Price	Stock	Quantity
1 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 420	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 670	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Citrulline-d₇:

L-Citrulline In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

182.23

Formula

C₆H₆D₇N₃O₃

CAS No.

2483831-24-7

Unlabeled CAS

372-75-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C(N)([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 50 mg/mL (274.38 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.4876 mL	27.4379 mL	54.8757 mL
5 mM	1.0975 mL	5.4876 mL	10.9751 mL
10 mM	0.5488 mL	2.7438 mL	5.4876 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (273 KB) SDS (251 KB)

COA (249 KB) HNMR (495 KB) RP-HPLC (664 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Fleszar MG, et al. Quantitative Analysis of l-Arginine, Dimethylated Arginine Derivatives, l-Citrulline, and Dimethylamine in Human Serum Using Liquid Chromatography-Mass Spectrometric Method. Chromatographia. 2018;81(6):911-921. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O	1 mM	5.4876 mL	27.4379 mL	54.8757 mL	137.1893 mL
	5 mM	1.0975 mL	5.4876 mL	10.9751 mL	27.4379 mL
	10 mM	0.5488 mL	2.7438 mL	5.4876 mL	13.7189 mL
	15 mM	0.3658 mL	1.8292 mL	3.6584 mL	9.1460 mL
	20 mM	0.2744 mL	1.3719 mL	2.7438 mL	6.8595 mL
	25 mM	0.2195 mL	1.0975 mL	2.1950 mL	5.4876 mL
	30 mM	0.1829 mL	0.9146 mL	1.8292 mL	4.5730 mL
	40 mM	0.1372 mL	0.6859 mL	1.3719 mL	3.4297 mL
	50 mM	0.1098 mL	0.5488 mL	1.0975 mL	2.7438 mL
	60 mM	0.0915 mL	0.4573 mL	0.9146 mL	2.2865 mL
	80 mM	0.0686 mL	0.3430 mL	0.6859 mL	1.7149 mL
	100 mM	0.0549 mL	0.2744 mL	0.5488 mL	1.3719 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.