2. Metabolic Enzyme/Protease Neuronal Signaling Membrane Transporter/Ion Channel Apoptosis
  3. Endogenous Metabolite iGluR Ferroptosis Apoptosis
  4. L-Glutamic acid-13C5

L-Glutamic acid-13C5 is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

For research use only. We do not sell to patients.

L-Glutamic acid-<sup>13</sup>C<sub>5</sub> Chemical Structure

L-Glutamic acid-13C5 Chemical Structure

CAS No. : 55443-55-5

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5 mg USD 270 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Glutamic acid-13C5:

L-Glutamic acid-13C5 Related Antibodies

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

L-Glutamic acid-13C5 is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

IC50 & Target

NMDA Receptor

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Glutamic acid-13C5 Related Antibodies
Molecular Weight

152.09

Formula

13C5H9NO4
CAS No.
Unlabeled CAS

56-86-0
Appearance

Solid

Color

White to off-white

SMILES

O[13C]([13CH2][13CH2][13C@H](N)[13C](O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5 mg/mL (32.88 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.5751 mL 32.8753 mL 65.7505 mL
5 mM 1.3150 mL 6.5751 mL 13.1501 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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In Vivo Dissolution Calculator
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The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.5751 mL 32.8753 mL 65.7505 mL 164.3764 mL
5 mM 1.3150 mL 6.5751 mL 13.1501 mL 32.8753 mL
10 mM 0.6575 mL 3.2875 mL 6.5751 mL 16.4376 mL
15 mM 0.4383 mL 2.1917 mL 4.3834 mL 10.9584 mL
20 mM 0.3288 mL 1.6438 mL 3.2875 mL 8.2188 mL
25 mM 0.2630 mL 1.3150 mL 2.6300 mL 6.5751 mL
30 mM 0.2192 mL 1.0958 mL 2.1917 mL 5.4792 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Glutamic acid-13C5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Glutamic acid-13C555443-55-5Endogenous MetaboliteiGluRFerroptosisApoptosisIonotropic glutamate receptorsInhibitorinhibitorinhibit

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