L-Lysine-¹⁵N₂ hydrochloride

Name: L-Lysine- 15 N 2 hydrochloride
Brand: MedChemExpress
SKU: HY-N0470S
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0470S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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L-Lysine-¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.

For research use only. We do not sell to patients.

L-Lysine-<sup>15</sup>N<sub>2</sub> hydrochloride Chemical Structure

L-Lysine-¹⁵N₂ hydrochloride Chemical Structure

CAS No. : 1217460-44-0

Size	Price	Stock	Quantity
5 mg	USD 210	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Lysine-¹⁵N₂ hydrochloride:

L-Lysine hydrochloride In-stock
L-Lysine13C6,15N2 Get quote
L-Lysine-¹³C₆,¹⁵N₂ hydrochloride Get quote
L-Lysine-¹³C₆,¹⁵N₂ dihydrochloride Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

184.64

Formula

C₆H₁₅Cl¹⁵N₂O₂

CAS No.

1217460-44-0

Unlabeled CAS

657-27-2

Appearance

Solid

Color

White to off-white

SMILES

[15NH2]CCCC[C@H]([15NH2])C(O)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 62.5 mg/mL (338.50 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.4159 mL	27.0797 mL	54.1594 mL
5 mM	1.0832 mL	5.4159 mL	10.8319 mL
10 mM	0.5416 mL	2.7080 mL	5.4159 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (245 KB) HNMR (254 KB) MS (69 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [Content Brief]

[3]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul;26(7):999-1009. [Content Brief]

[4]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.4159 mL	27.0797 mL	54.1594 mL	135.3986 mL
	5 mM	1.0832 mL	5.4159 mL	10.8319 mL	27.0797 mL
	10 mM	0.5416 mL	2.7080 mL	5.4159 mL	13.5399 mL
	15 mM	0.3611 mL	1.8053 mL	3.6106 mL	9.0266 mL
	20 mM	0.2708 mL	1.3540 mL	2.7080 mL	6.7699 mL
	25 mM	0.2166 mL	1.0832 mL	2.1664 mL	5.4159 mL
	30 mM	0.1805 mL	0.9027 mL	1.8053 mL	4.5133 mL
	40 mM	0.1354 mL	0.6770 mL	1.3540 mL	3.3850 mL
	50 mM	0.1083 mL	0.5416 mL	1.0832 mL	2.7080 mL
	60 mM	0.0903 mL	0.4513 mL	0.9027 mL	2.2566 mL
	80 mM	0.0677 mL	0.3385 mL	0.6770 mL	1.6925 mL
	100 mM	0.0542 mL	0.2708 mL	0.5416 mL	1.3540 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.