L-Methionine-¹³C,d₃

Name: L-Methionine- 13 C,d 3
Brand: MedChemExpress
SKU: HY-N0326S2
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0326S2 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Methionine-¹³C,d₃ is the ¹³C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

For research use only. We do not sell to patients.

L-Methionine-<sup>13</sup>C,d<sub>3</sub> Chemical Structure

L-Methionine-¹³C,d₃ Chemical Structure

CAS No. : 73488-65-0

Size	Price	Stock	Quantity
5 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 85	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 166	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 266	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 426	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 766	Get quote	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Methionine-¹³C,d₃:

L-Methionine In-stock

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

153.22

Formula

C₄¹³CH₈D₃NO₂S

CAS No.

73488-65-0

Unlabeled CAS

63-68-3

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCS[13C]([2H])([2H])[2H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 16.67 mg/mL (108.80 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.5266 mL	32.6328 mL	65.2656 mL
5 mM	1.3053 mL	6.5266 mL	13.0531 mL
10 mM	0.6527 mL	3.2633 mL	6.5266 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (247 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O	1 mM	6.5266 mL	32.6328 mL	65.2656 mL	163.1641 mL
	5 mM	1.3053 mL	6.5266 mL	13.0531 mL	32.6328 mL
	10 mM	0.6527 mL	3.2633 mL	6.5266 mL	16.3164 mL
	15 mM	0.4351 mL	2.1755 mL	4.3510 mL	10.8776 mL
	20 mM	0.3263 mL	1.6316 mL	3.2633 mL	8.1582 mL
	25 mM	0.2611 mL	1.3053 mL	2.6106 mL	6.5266 mL
	30 mM	0.2176 mL	1.0878 mL	2.1755 mL	5.4388 mL
	40 mM	0.1632 mL	0.8158 mL	1.6316 mL	4.0791 mL
	50 mM	0.1305 mL	0.6527 mL	1.3053 mL	3.2633 mL
	60 mM	0.1088 mL	0.5439 mL	1.0878 mL	2.7194 mL
	80 mM	0.0816 mL	0.4079 mL	0.8158 mL	2.0396 mL
	100 mM	0.0653 mL	0.3263 mL	0.6527 mL	1.6316 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.