L-Methionine-¹³C,d₅

Name: L-Methionine- 13 C,d 5
Brand: MedChemExpress
SKU: HY-N0326S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0326S1 Purity: 98%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Methionine-¹³C,d₅ is the ¹³C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

For research use only. We do not sell to patients.

L-Methionine-<sup>13</sup>C,d<sub>5</sub> Chemical Structure

L-Methionine-¹³C,d₅ Chemical Structure

CAS No. : 2483824-33-3

Size	Price	Stock	Quantity
1 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Methionine-¹³C,d₅:

L-Methionine In-stock

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

155.23

Formula

C₄¹³CH₆D₅NO₂S

CAS No.

2483824-33-3

Unlabeled CAS

63-68-3

Appearance

Solid

Color

White to off-white

SMILES

OC([C@](N)([2H])C([2H])([2H])C([2H])([2H])S[13CH3])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 10 mg/mL (64.42 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.4421 mL	32.2103 mL	64.4205 mL
5 mM	1.2884 mL	6.4421 mL	12.8841 mL
10 mM	0.6442 mL	3.2210 mL	6.4421 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (249 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.4421 mL	32.2103 mL	64.4205 mL	161.0513 mL
	5 mM	1.2884 mL	6.4421 mL	12.8841 mL	32.2103 mL
	10 mM	0.6442 mL	3.2210 mL	6.4421 mL	16.1051 mL
	15 mM	0.4295 mL	2.1474 mL	4.2947 mL	10.7368 mL
	20 mM	0.3221 mL	1.6105 mL	3.2210 mL	8.0526 mL
	25 mM	0.2577 mL	1.2884 mL	2.5768 mL	6.4421 mL
	30 mM	0.2147 mL	1.0737 mL	2.1474 mL	5.3684 mL
	40 mM	0.1611 mL	0.8053 mL	1.6105 mL	4.0263 mL
	50 mM	0.1288 mL	0.6442 mL	1.2884 mL	3.2210 mL
	60 mM	0.1074 mL	0.5368 mL	1.0737 mL	2.6842 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.