1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Endogenous Metabolite
  3. L-Methionine-13C,d5

L-Methionine-13C,d5 is the 13C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

For research use only. We do not sell to patients.

L-Methionine-<sup>13</sup>C,d<sub>5</sub> Chemical Structure

L-Methionine-13C,d5 Chemical Structure

CAS No. : 2483824-33-3

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Based on 1 publication(s) in Google Scholar

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Description

L-Methionine-13C,d5 is the 13C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

155.23

Formula

C413CH6D5NO2S

CAS No.
Unlabeled CAS

63-68-3

Appearance

Solid

Color

White to off-white

SMILES

OC([C@](N)([2H])C([2H])([2H])C([2H])([2H])S[13CH3])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (64.42 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4421 mL 32.2103 mL 64.4205 mL
5 mM 1.2884 mL 6.4421 mL 12.8841 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.4421 mL 32.2103 mL 64.4205 mL 161.0513 mL
5 mM 1.2884 mL 6.4421 mL 12.8841 mL 32.2103 mL
10 mM 0.6442 mL 3.2210 mL 6.4421 mL 16.1051 mL
15 mM 0.4295 mL 2.1474 mL 4.2947 mL 10.7368 mL
20 mM 0.3221 mL 1.6105 mL 3.2210 mL 8.0526 mL
25 mM 0.2577 mL 1.2884 mL 2.5768 mL 6.4421 mL
30 mM 0.2147 mL 1.0737 mL 2.1474 mL 5.3684 mL
40 mM 0.1611 mL 0.8053 mL 1.6105 mL 4.0263 mL
50 mM 0.1288 mL 0.6442 mL 1.2884 mL 3.2210 mL
60 mM 0.1074 mL 0.5368 mL 1.0737 mL 2.6842 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Methionine-13C,d5
Cat. No.:
HY-N0326S1
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