L-Methionine-d₃

Name: L-Methionine-d 3
Brand: MedChemExpress
SKU: HY-N0326S7
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0326S7 Purity: 99.90%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Methionine-d₃ is the deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

For research use only. We do not sell to patients.

L-Methionine-d<sub>3</sub> Chemical Structure

L-Methionine-d₃ Chemical Structure

CAS No. : 13010-53-2

Size	Price	Stock	Quantity
50 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Methionine-d₃:

L-Methionine In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

L-Methionine-d₃ is the deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

152.23

Formula

C₅H₈D₃NO₂S

CAS No.

13010-53-2

Unlabeled CAS

63-68-3

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCSC([2H])([2H])[2H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 20 mg/mL (131.38 mM; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.5690 mL	32.8450 mL	65.6901 mL
5 mM	1.3138 mL	6.5690 mL	13.1380 mL
10 mM	0.6569 mL	3.2845 mL	6.5690 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.90%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (245 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.5690 mL	32.8450 mL	65.6901 mL	164.2252 mL
	5 mM	1.3138 mL	6.5690 mL	13.1380 mL	32.8450 mL
	10 mM	0.6569 mL	3.2845 mL	6.5690 mL	16.4225 mL
	15 mM	0.4379 mL	2.1897 mL	4.3793 mL	10.9483 mL
	20 mM	0.3285 mL	1.6423 mL	3.2845 mL	8.2113 mL
	25 mM	0.2628 mL	1.3138 mL	2.6276 mL	6.5690 mL
	30 mM	0.2190 mL	1.0948 mL	2.1897 mL	5.4742 mL
	40 mM	0.1642 mL	0.8211 mL	1.6423 mL	4.1056 mL
	50 mM	0.1314 mL	0.6569 mL	1.3138 mL	3.2845 mL
	60 mM	0.1095 mL	0.5474 mL	1.0948 mL	2.7371 mL
	80 mM	0.0821 mL	0.4106 mL	0.8211 mL	2.0528 mL
	100 mM	0.0657 mL	0.3285 mL	0.6569 mL	1.6423 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.