L-Ornithine-d₂ hydrochloride

Name: L-Ornithine-d 2 hydrochloride
Brand: MedChemExpress
SKU: HY-W017018S3
Rating: 4.5 (1 reviews)

Cat. No.: HY-W017018S3 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Ornithine-d₂ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

For research use only. We do not sell to patients.

L-Ornithine-d<sub>2</sub> hydrochloride Chemical Structure

L-Ornithine-d₂ hydrochloride Chemical Structure

CAS No. : 2483831-42-9

Size	Price	Stock	Quantity
1 mg	USD 224	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 560	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 900	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1800	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Ornithine-d₂ hydrochloride:

L-Ornithine hydrochloride Get quote

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

170.63

Formula

C₅H₁₁D₂ClN₂O₂

CAS No.

2483831-42-9

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCC([2H])([2H])N)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (293.03 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8606 mL	29.3032 mL	58.6063 mL
5 mM	1.1721 mL	5.8606 mL	11.7213 mL
10 mM	0.5861 mL	2.9303 mL	5.8606 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (247 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O	1 mM	5.8606 mL	29.3032 mL	58.6063 mL	146.5158 mL
	5 mM	1.1721 mL	5.8606 mL	11.7213 mL	29.3032 mL
	10 mM	0.5861 mL	2.9303 mL	5.8606 mL	14.6516 mL
	15 mM	0.3907 mL	1.9535 mL	3.9071 mL	9.7677 mL
	20 mM	0.2930 mL	1.4652 mL	2.9303 mL	7.3258 mL
	25 mM	0.2344 mL	1.1721 mL	2.3443 mL	5.8606 mL
	30 mM	0.1954 mL	0.9768 mL	1.9535 mL	4.8839 mL
	40 mM	0.1465 mL	0.7326 mL	1.4652 mL	3.6629 mL
	50 mM	0.1172 mL	0.5861 mL	1.1721 mL	2.9303 mL
	60 mM	0.0977 mL	0.4884 mL	0.9768 mL	2.4419 mL
	80 mM	0.0733 mL	0.3663 mL	0.7326 mL	1.8314 mL
	100 mM	0.0586 mL	0.2930 mL	0.5861 mL	1.4652 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.