1. Apoptosis Metabolic Enzyme/Protease
  2. Apoptosis Endogenous Metabolite
  3. L-Theanine-d5

L-Theanine-d5  (Synonyms: L-Glutamic Acid γ-ethyl amide-d5; Nγ-Ethyl-L-glutamine-d5)

Cat. No.: HY-15121S Purity: 99%
SDS COA Handling Instructions

L-Theanine-d5 is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide)is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

For research use only. We do not sell to patients.

L-Theanine-d<sub>5</sub> Chemical Structure

L-Theanine-d5 Chemical Structure

CAS No. : 1217451-85-8

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1 mg USD 240 In-stock
5 mg USD 600 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

L-Theanine-d5 is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide)is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

179.23

Formula

C7H9D5N2O3

CAS No.
Unlabeled CAS

3081-61-6

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCC(NC([2H])([2H])C([2H])([2H])[2H])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 150 mg/mL (836.91 mM; Need ultrasonic and warming)

PBS (pH 7.2) : ≥ 10 mg/mL (55.79 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5794 mL 27.8971 mL 55.7942 mL
5 mM 1.1159 mL 5.5794 mL 11.1588 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
PBS (pH 7.2) / H2O 1 mM 5.5794 mL 27.8971 mL 55.7942 mL 139.4856 mL
5 mM 1.1159 mL 5.5794 mL 11.1588 mL 27.8971 mL
10 mM 0.5579 mL 2.7897 mL 5.5794 mL 13.9486 mL
15 mM 0.3720 mL 1.8598 mL 3.7196 mL 9.2990 mL
20 mM 0.2790 mL 1.3949 mL 2.7897 mL 6.9743 mL
25 mM 0.2232 mL 1.1159 mL 2.2318 mL 5.5794 mL
30 mM 0.1860 mL 0.9299 mL 1.8598 mL 4.6495 mL
40 mM 0.1395 mL 0.6974 mL 1.3949 mL 3.4871 mL
50 mM 0.1116 mL 0.5579 mL 1.1159 mL 2.7897 mL
H2O 60 mM 0.0930 mL 0.4650 mL 0.9299 mL 2.3248 mL
80 mM 0.0697 mL 0.3487 mL 0.6974 mL 1.7436 mL
100 mM 0.0558 mL 0.2790 mL 0.5579 mL 1.3949 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Product Name:
L-Theanine-d5
Cat. No.:
HY-15121S
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