L-Threonine-¹³C₄

Name: L-Threonine- 13 C 4
Brand: MedChemExpress
SKU: HY-N0658S6
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0658S6 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Threonine-¹³C₄ is the ¹³C labeled L-Threonine[1]. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[2].

For research use only. We do not sell to patients.

L-Threonine-<sup>13</sup>C<sub>4</sub> Chemical Structure

L-Threonine-¹³C₄ Chemical Structure

CAS No. : 55443-53-3

Size	Price	Stock	Quantity
1 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Threonine-¹³C₄:

L-Threonine Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

L-Threonine-¹³C₄ is the ¹³C labeled L-Threonine[1]. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

123.09

Formula

¹³C₄H₉NO₃

CAS No.

55443-53-3

Unlabeled CAS

72-19-5

Appearance

Solid

Color

White to off-white

SMILES

N[13C@H]([13C](O)=O)[13C@@H]([13CH3])O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (1015.52 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.1241 mL	40.6207 mL	81.2414 mL
5 mM	1.6248 mL	8.1241 mL	16.2483 mL
10 mM	0.8124 mL	4.0621 mL	8.1241 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (248 KB) HNMR (241 KB) MS (76 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	8.1241 mL	40.6207 mL	81.2414 mL	203.1034 mL
	5 mM	1.6248 mL	8.1241 mL	16.2483 mL	40.6207 mL
	10 mM	0.8124 mL	4.0621 mL	8.1241 mL	20.3103 mL
	15 mM	0.5416 mL	2.7080 mL	5.4161 mL	13.5402 mL
	20 mM	0.4062 mL	2.0310 mL	4.0621 mL	10.1552 mL
	25 mM	0.3250 mL	1.6248 mL	3.2497 mL	8.1241 mL
	30 mM	0.2708 mL	1.3540 mL	2.7080 mL	6.7701 mL
	40 mM	0.2031 mL	1.0155 mL	2.0310 mL	5.0776 mL
	50 mM	0.1625 mL	0.8124 mL	1.6248 mL	4.0621 mL
	60 mM	0.1354 mL	0.6770 mL	1.3540 mL	3.3851 mL
	80 mM	0.1016 mL	0.5078 mL	1.0155 mL	2.5388 mL
	100 mM	0.0812 mL	0.4062 mL	0.8124 mL	2.0310 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.