L-Threonine-¹⁵N

Name: L-Threonine- 15 N
Brand: MedChemExpress
SKU: HY-N0658S
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0658S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Threonine-¹⁵N is the ¹⁵N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1][2].

For research use only. We do not sell to patients.

L-Threonine-<sup>15</sup>N Chemical Structure

L-Threonine-¹⁵N Chemical Structure

CAS No. : 80681-09-0

Size	Price	Stock	Quantity
5 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 440	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Threonine-¹⁵N:

L-Threonine Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

L-Threonine-¹⁵N is the ¹⁵N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

120.11

Formula

C₄H₉¹⁵NO₃

CAS No.

80681-09-0

Unlabeled CAS

72-19-5

Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](O)[C@H]([15NH2])C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 33.33 mg/mL (277.50 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.3257 mL	41.6285 mL	83.2570 mL
5 mM	1.6651 mL	8.3257 mL	16.6514 mL
10 mM	0.8326 mL	4.1629 mL	8.3257 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O	1 mM	8.3257 mL	41.6285 mL	83.2570 mL	208.1425 mL
	5 mM	1.6651 mL	8.3257 mL	16.6514 mL	41.6285 mL
	10 mM	0.8326 mL	4.1629 mL	8.3257 mL	20.8143 mL
	15 mM	0.5550 mL	2.7752 mL	5.5505 mL	13.8762 mL
	20 mM	0.4163 mL	2.0814 mL	4.1629 mL	10.4071 mL
	25 mM	0.3330 mL	1.6651 mL	3.3303 mL	8.3257 mL
	30 mM	0.2775 mL	1.3876 mL	2.7752 mL	6.9381 mL
	40 mM	0.2081 mL	1.0407 mL	2.0814 mL	5.2036 mL
	50 mM	0.1665 mL	0.8326 mL	1.6651 mL	4.1629 mL
	60 mM	0.1388 mL	0.6938 mL	1.3876 mL	3.4690 mL
	80 mM	0.1041 mL	0.5204 mL	1.0407 mL	2.6018 mL
	100 mM	0.0833 mL	0.4163 mL	0.8326 mL	2.0814 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.