L18-MDP 

L18-MDP is a derivative of muramyl dipeptide, an antibacterial agent. L18-MDP has antibacterial activity and has potential applications in bacterial and fungal infections^[1].

L18-MDP (100 µg; s.c.; single dose) has anti-infection effect in mice infected with Escherichia coli or Klebsiella pneumoniae^[1].
L18-MDP (100 µg or 1000 µg; s.c., i.p., i.v. or p.o.; single dose) increases the survival rate of mice infected with Escherichia coli and improves the pathological tissue of mice infected with Listeria monocytogenes^[1].
L18-MDP (100 µg or 200 µg; s.c. or i.p.; once daily for 3 days) increases the survival rate of mice infected with Candida albicans^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

758.94

C₃₇H₆₆N₄O₁₂

60398-08-5

Ac-(6-O-stearoyl)-muramyl-Ala-{d-Glu}-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Osada Y, et al. Effect of L18-MDP(Ala), a synthetic derivative of muramyl dipeptide, on nonspecific resistance of mice to microbial infections. Infect Immun. 1982 Jul;37(1):292-300.  [Content Brief]