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  3. Lactyl-CoA

Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers.

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Lactyl-CoA Chemical Structure

Lactyl-CoA Chemical Structure

CAS No. : 1926-57-4

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1 mg USD 580 In-stock
5 mg USD 1450 In-stock
10 mg USD 2300 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers[1].

Molecular Weight

839.60

Formula

C24H40N7O18P3S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(C(O)C)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (119.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (59.55 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1910 mL 5.9552 mL 11.9104 mL
5 mM 0.2382 mL 1.1910 mL 2.3821 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.1910 mL 5.9552 mL 11.9104 mL 29.7761 mL
5 mM 0.2382 mL 1.1910 mL 2.3821 mL 5.9552 mL
10 mM 0.1191 mL 0.5955 mL 1.1910 mL 2.9776 mL
15 mM 0.0794 mL 0.3970 mL 0.7940 mL 1.9851 mL
20 mM 0.0596 mL 0.2978 mL 0.5955 mL 1.4888 mL
25 mM 0.0476 mL 0.2382 mL 0.4764 mL 1.1910 mL
30 mM 0.0397 mL 0.1985 mL 0.3970 mL 0.9925 mL
40 mM 0.0298 mL 0.1489 mL 0.2978 mL 0.7444 mL
50 mM 0.0238 mL 0.1191 mL 0.2382 mL 0.5955 mL
DMSO 60 mM 0.0199 mL 0.0993 mL 0.1985 mL 0.4963 mL
80 mM 0.0149 mL 0.0744 mL 0.1489 mL 0.3722 mL
100 mM 0.0119 mL 0.0596 mL 0.1191 mL 0.2978 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lactyl-CoA
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HY-141540
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