2. Inhibitory Antibodies
  3. Landogrozumab

Landogrozumab  (Synonyms: LY2495655; Anti-GDF8 / Myostatin Reference Antibody (landogrozumab))

Cat. No.: HY-P99370 Purity: 99.54%
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Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease.

For research use only. We do not sell to patients.

CAS No. : 1391726-30-9

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1 mg USD 350 In-stock
5 mg USD 910 In-stock
10 mg USD 1450 In-stock
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Based on 1 publication(s) in Google Scholar

Landogrozumab Related Antibodies

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Description

Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease[1].

Isotype

Human IgG4 kappa
Recommend Isotype Controls
Species

Humanized
In Vivo

Landogrozumab (3 and 15 mg/kg; i.v. once) affects muscle mass of aged mice with duchenne muscular dystrophy[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Duchenne muscular dystrophy (DMD) C57BL/10-mdx mouse model[1]
Dosage: 3 and 50 mg/kg
Administration: Intravenous injection; 3 and 50 mg/kg once
Result: Increasesd muscle mass of aged mice at a dose of 50 mg/kg while 3 mg/kg showed no significant effects.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Landogrozumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Purity & Documentation
References
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Landogrozumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Landogrozumab1391726-30-9LY2495655 Anti-GDF8 / Myostatin Reference Antibody (landogrozumab)LY 2495655LY-2495655Othersmuscle volumehand grip strengthmuscle wastingmuscle massmiceduchenne muscular dystrophyInhibitorinhibitorinhibit

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