2. Anti-infection
  3. Antibiotic
  4. Lankacidinol

Lankacidinol (T-2636 F) is an antibiotic. Lankacidinol and its related metabolites 2,18-seco-lankacidinol A (1) and 2,18-seco-lankacidinol B (2) have significant biological activities and potential medicinal value. In addition, 2,18-seco-lankacidinol A exhibits potent antitumor activity.

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Lankacidinol Chemical Structure

Lankacidinol Chemical Structure

CAS No. : 23498-37-5

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Lankacidinol Related Antibodies

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Description

Lankacidinol (T-2636 F) is an antibiotic. Lankacidinol and its related metabolites 2,18-seco-lankacidinol A (1) and 2,18-seco-lankacidinol B (2) have significant biological activities and potential medicinal value. In addition, 2,18-seco-lankacidinol A exhibits potent antitumor activity.

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 100 μM
Compound: 3
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 34883453]
HeLa IC50
24.8 μM
Compound: 3
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 34883453]
MCF7 IC50
75.7 μM
Compound: 3
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 34883453]
Molecular Weight

461.55

Formula

C25H35NO7
CAS No.
SMILES

O[C@@H](C(N[C@@H]([C@](C)1C([C@@H]2C)=O)/C=C(/C=C/[C@H](C/C=C(/C=C/[C@H](C[C@]2(OC1=O)[H])O)C)O)C)=O)C
Initial Source

Streptomyces sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lankacidinol Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lankacidinol23498-37-5T-2636 FAntibioticInhibitorinhibitorinhibit

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HY-117183
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