Lariciresinol

Cat. No.: HY-N3405 Purity: 99.79%: FAQs
Data Sheet SDS COA Handling Instructions

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Lariciresinol is a compound isolated from Arabidopsis thaliana.

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Lariciresinol Chemical Structure

CAS No. : 27003-73-2

Size	Price	Stock	Quantity
1 mg	USD 210	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Lariciresinol is a compound isolated from Arabidopsis thaliana^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	> 30 μM Compound: 4	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 26988298]
A549	IC₅₀	24.51 μM Compound: 4	Anticancer activity against human A549 cells by SRB assay Anticancer activity against human A549 cells by SRB assay	[PMID: 21420296]
BV-2	IC₅₀	72.58 μM Compound: 4	Anti-neuroinflammatory activity in LPS-activated mouse BV2 cells assessed as inhibition of NO production after 24 hrs by Griess assay Anti-neuroinflammatory activity in LPS-activated mouse BV2 cells assessed as inhibition of NO production after 24 hrs by Griess assay	[PMID: 26988298]
RAW264.7	IC₅₀	> 50 μM Compound: 22	Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method	[PMID: 24035341]
RAW264.7	IC₅₀	> 50 μM Compound: 20	Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay	[PMID: 33939429]
RAW264.7	IC₅₀	0.252 mM Compound: 14	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs	[PMID: 18986199]
SK-MEL-2	IC₅₀	> 30 μM Compound: 4	Cytotoxicity against human SK-MEL-2 cells by SRB assay Cytotoxicity against human SK-MEL-2 cells by SRB assay	[PMID: 26988298]
SK-MEL-2	IC₅₀	> 30 μM Compound: 4	Anticancer activity against human SK-MEL-2 cells by SRB assay Anticancer activity against human SK-MEL-2 cells by SRB assay	[PMID: 21420296]
SK-OV-3	IC₅₀	> 30 μM Compound: 4	Cytotoxicity against human SKOV3 cells by SRB assay Cytotoxicity against human SKOV3 cells by SRB assay	[PMID: 26988298]
SK-OV-3	IC₅₀	> 30 μM Compound: 4	Anticancer activity against human SKOV3 cells by SRB assay Anticancer activity against human SKOV3 cells by SRB assay	[PMID: 21420296]
XF498	IC₅₀	> 30 μM Compound: 4	Cytotoxicity against human XF498 cells by SRB assay Cytotoxicity against human XF498 cells by SRB assay	[PMID: 26988298]
XF498	IC₅₀	11.65 μM Compound: 4	Anticancer activity against human XF498 cells by SRB assay Anticancer activity against human XF498 cells by SRB assay	[PMID: 21420296]

Molecular Weight

360.40

Formula

C₂₀H₂₄O₆

CAS No.

27003-73-2

Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@](C(C=C2)=CC(OC)=C2O)([H])OC[C@@H]1CC(C=C3)=CC(OC)=C3O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (277.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Methanol : 25 mg/mL (69.37 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7747 mL	13.8735 mL	27.7469 mL
5 mM	0.5549 mL	2.7747 mL	5.5494 mL
10 mM	0.2775 mL	1.3873 mL	2.7747 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.79%

Select Batch:

Data Sheet (269 KB) SDS (398 KB)

COA (250 KB) HNMR (271 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

References

[1]. Nakatsubo T, et al. Characterization of Arabidopsis thaliana pinoresinol reductase, a new type of enzyme involved in lignan biosynthesis. J Biol Chem. 2008;283(23):15550-15557. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Methanol / DMSO	1 mM	2.7747 mL	13.8735 mL	27.7469 mL	69.3674 mL
	5 mM	0.5549 mL	2.7747 mL	5.5494 mL	13.8735 mL
	10 mM	0.2775 mL	1.3873 mL	2.7747 mL	6.9367 mL
	15 mM	0.1850 mL	0.9249 mL	1.8498 mL	4.6245 mL
	20 mM	0.1387 mL	0.6937 mL	1.3873 mL	3.4684 mL
	25 mM	0.1110 mL	0.5549 mL	1.1099 mL	2.7747 mL
	30 mM	0.0925 mL	0.4624 mL	0.9249 mL	2.3122 mL
	40 mM	0.0694 mL	0.3468 mL	0.6937 mL	1.7342 mL
	50 mM	0.0555 mL	0.2775 mL	0.5549 mL	1.3873 mL
	60 mM	0.0462 mL	0.2312 mL	0.4624 mL	1.1561 mL
DMSO	80 mM	0.0347 mL	0.1734 mL	0.3468 mL	0.8671 mL
DMSO	100 mM	0.0277 mL	0.1387 mL	0.2775 mL	0.6937 mL

Lariciresinol Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lariciresinol27003-73-2OthersInhibitorinhibitorinhibit

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Lariciresinol

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