2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. LAS191859

LAS191859 is an orally active, potent and selective CRTh2 antagonist with an IC50 of 9.58 nM against human CRTh2. LAS191859 can be used for the research of chronic asthma.

For research use only. We do not sell to patients.

LAS191859 Chemical Structure

LAS191859 Chemical Structure

CAS No. : 1420071-13-1

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LAS191859 Related Antibodies

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Description

LAS191859 is an orally active, potent and selective CRTh2 antagonist with an IC50 of 9.58 nM against human CRTh2. LAS191859 can be used for the research of chronic asthma[1].

IC50 & Target

IC50: 7.6 nM (guinea pig CRTh2), 9.58 nM (human CRTh2), 14 nM (rat CRTh2), 15.5 nM (mouse CRTh2)[1]
Molecular Weight

459.46

Formula

C24H24F3N3O3
CAS No.
SMILES

CCN(CC1=CC(C(F)(F)F)=CC=C1N2C=C(C3=C2N=C(C=C3)C)CC(O)=O)C(C4CC4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LAS191859 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LAS1918591420071-13-1LAS 191859LAS-191859Prostaglandin ReceptorCHO-K1systemic eosinophiliaguinea pigInhibitorinhibitorinhibit

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LAS191859
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HY-123596
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