2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. LBG30300

LBG30300 is a subtype-selective mGlu2 receptor agonist EC50 0.6 nM. LBG30300 is blood-brain barrier permeable.

For research use only. We do not sell to patients.

LBG30300 Chemical Structure

LBG30300 Chemical Structure

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LBG30300 Related Antibodies

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mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR

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Description

LBG30300 is a subtype-selective mGlu2 receptor agonist EC50 0.6 nM. LBG30300 is blood-brain barrier permeable[1].

IC50 & Target

mGlu2 Receptor

0.6 nM (EC50)

mGluR3

0.373 μM (EC50)

mGlu4

0.11 μM (EC50)

mGlu6

0.28 μM (EC50)

mGlu8 Receptor

0.097 μM (EC50)

Molecular Weight

217.18

Formula

C8H11NO6
SMILES

O=C([C@@H]1[C@@H]([C@H](N)C(O)=O)[C@@H]1CC(O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LBG30300 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LBG30300LBG 30300LBG-30300mGluRMetabotropic glutamate receptorsMetabotropic glutamate (Glu)Excitatory neurotransmission,Inhibitorinhibitorinhibit

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