2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Lenalidomide 4'-PEG1-azide

Lenalidomide 4'-PEG1-azide (Compound 4g) is a lenalidomide-derived azide. Lenalidomide 4'-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide 4'-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups..

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Lenalidomide 4'-PEG1-azide Chemical Structure

Lenalidomide 4'-PEG1-azide Chemical Structure

CAS No. : 2399455-45-7

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Lenalidomide 4'-PEG1-azide Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

Lenalidomide 4'-PEG1-azide (Compound 4g) is a lenalidomide-derived azide. Lenalidomide 4'-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide 4'-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.[1].

Molecular Weight

372.38

Formula

C17H20N6O4
CAS No.
SMILES

[N-]=[N+]=NCCOCCNC1=CC=CC2=C1CN(C3C(NC(CC3)=O)=O)C2=O
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References
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Lenalidomide 4'-PEG1-azide Related Classifications

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Keywords:

Lenalidomide 4'-PEG1-azide2399455-45-7E3 Ligase Ligand-Linker Conjugateslenalidomideclick chemistryInhibitorinhibitorinhibit

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