2. Others Membrane Transporter/Ion Channel Neuronal Signaling
  3. Isotope-Labeled Compounds Calcium Channel
  4. Lercanidipine-d3 hydrochloride

Lercanidipine-d3 hydrochloride 

Cat. No.: HY-B0612DS1 Purity: 98.14%
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Lercanidipine-d3 (hydrochloride) is the deuterium labeled Lercanidipine. Lercanidipine is a lipophilic third-generation dihydropyridine-calcium channel blocker (DHP-CCB). Lercanidipine has long lasting antihypertensive action and reno-protective effect[1][2][3].

For research use only. We do not sell to patients.

Lercanidipine-d<sub>3</sub> hydrochloride Chemical Structure

Lercanidipine-d3 hydrochloride Chemical Structure

CAS No. : 1189954-18-4

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Other Forms of Lercanidipine-d3 hydrochloride:

Lercanidipine-d3 hydrochloride Related Antibodies

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Description

Lercanidipine-d3 (hydrochloride) is the deuterium labeled Lercanidipine. Lercanidipine is a lipophilic third-generation dihydropyridine-calcium channel blocker (DHP-CCB). Lercanidipine has long lasting antihypertensive action and reno-protective effect[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lercanidipine-d3 hydrochloride Related Antibodies
Molecular Weight

651.21

Formula

C36H39D3ClN3O6
CAS No.
Unlabeled CAS

132866-11-6
Appearance

Solid

Color

Light yellow to yellow

SMILES

C(OC(CN(CCC(C1=CC=CC=C1)C2=CC=CC=C2)C([2H])([2H])[2H])(C)C)(=O)C=3C(C(C(OC)=O)=C(C)NC3C)C4=CC(N(=O)=O)=CC=C4.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (30.71 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5356 mL 7.6780 mL 15.3560 mL
5 mM 0.3071 mL 1.5356 mL 3.0712 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5356 mL 7.6780 mL 15.3560 mL 38.3901 mL
5 mM 0.3071 mL 1.5356 mL 3.0712 mL 7.6780 mL
10 mM 0.1536 mL 0.7678 mL 1.5356 mL 3.8390 mL
15 mM 0.1024 mL 0.5119 mL 1.0237 mL 2.5593 mL
20 mM 0.0768 mL 0.3839 mL 0.7678 mL 1.9195 mL
25 mM 0.0614 mL 0.3071 mL 0.6142 mL 1.5356 mL
30 mM 0.0512 mL 0.2559 mL 0.5119 mL 1.2797 mL
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Lercanidipine-d3 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lercanidipine-d31189954-18-4Isotope-Labeled CompoundsCalcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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