2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. [Leu31,Pro34]-Neuropeptide Y (porcine)

[Leu31,Pro34]-Neuropeptide Y (porcine) 

Cat. No.: HY-P0208 Purity: 98.40%
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[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects.

For research use only. We do not sell to patients.

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[Leu31,Pro34]-Neuropeptide Y (porcine) Chemical Structure

[Leu31,Pro34]-Neuropeptide Y (porcine) Chemical Structure

CAS No. : 125580-28-1

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1 mg USD 130 In-stock
5 mg USD 390 In-stock
10 mg USD 620 In-stock
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Based on 1 publication(s) in Google Scholar

[Leu31,Pro34]-Neuropeptide Y (porcine) Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE [Leu31,Pro34]-Neuropeptide Y (porcine)

View All Neuropeptide Y Receptor Isoform Specific Products:

View All Isoforms
NPY Y1 receptor NPY Y2 receptor NPY Y4 receptor NPY Y5 receptor

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects[1][2].

IC50 & Target[1]

NPY Y1 receptor

 

In Vivo

[Leu31,Pro34]-Neuropeptide Y (porcine) displaces radiolabeled NPY from cells that express Y1 receptors in a series of human neuroblastoma cell lines and on rat PC-12 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

4222.63

Formula

C190H286N54O56
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
Sequence Shortening

YPSKPDNPGEDAPAEDLARYYSALRHYINLLTRPRY-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (23.68 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.2368 mL 1.1841 mL 2.3682 mL
5 mM 0.0474 mL 0.2368 mL 0.4736 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.2368 mL 1.1841 mL 2.3682 mL 5.9205 mL
5 mM 0.0474 mL 0.2368 mL 0.4736 mL 1.1841 mL
10 mM 0.0237 mL 0.1184 mL 0.2368 mL 0.5920 mL
15 mM 0.0158 mL 0.0789 mL 0.1579 mL 0.3947 mL
20 mM 0.0118 mL 0.0592 mL 0.1184 mL 0.2960 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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[Leu31,Pro34]-Neuropeptide Y (porcine) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Leu31,Pro34]-Neuropeptide Y (porcine)125580-28-1Neuropeptide Y ReceptorNPY receptorNPYY1anxiolyticInhibitorinhibitorinhibit

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