Linoleic acid-¹³C₁₈

Name: Linoleic acid- 13 C 18
Brand: MedChemExpress
SKU: HY-N0729S2
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0729S2 Purity: 99.10%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Linoleic acid-¹³C₁₈ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

For research use only. We do not sell to patients.

Linoleic acid-<sup>13</sup>C<sub>18</sub> Chemical Structure

Linoleic acid-¹³C₁₈ Chemical Structure

CAS No. : 287111-25-5

Size	Price	Stock	Quantity
500 μg	USD 315	In-stock	Estimated Time of Arrival: December 31
1 mg	USD 520	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Linoleic acid-¹³C₁₈:

Linoleic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

298.31

Formula

¹³C₁₈H₃₂O₂

CAS No.

287111-25-5

Unlabeled CAS

60-33-3

Appearance

Liquid (Density: 0.957g/cm³)

Color

Colorless to light yellow

SMILES

O[13C]([13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2]/[13CH]=[13CH]\[13CH2]/[13CH]=[13CH]\[13CH2][13CH2][13CH2][13CH2][13CH3])=O

Shipping

Shipping with dry ice.

Storage

-80°C, protect from light, stored under nitrogen

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (335.22 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

0.1 M NaOH : 8.33 mg/mL (27.92 mM; ultrasonic and warming and adjust pH to 11 with NaOH)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3522 mL	16.7611 mL	33.5222 mL
5 mM	0.6704 mL	3.3522 mL	6.7044 mL
10 mM	0.3352 mL	1.6761 mL	3.3522 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.10%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

0.1 M NaOH / DMSO	1 mM	3.3522 mL	16.7611 mL	33.5222 mL	83.8054 mL
	5 mM	0.6704 mL	3.3522 mL	6.7044 mL	16.7611 mL
	10 mM	0.3352 mL	1.6761 mL	3.3522 mL	8.3805 mL
	15 mM	0.2235 mL	1.1174 mL	2.2348 mL	5.5870 mL
	20 mM	0.1676 mL	0.8381 mL	1.6761 mL	4.1903 mL
	25 mM	0.1341 mL	0.6704 mL	1.3409 mL	3.3522 mL
DMSO	30 mM	0.1117 mL	0.5587 mL	1.1174 mL	2.7935 mL
	40 mM	0.0838 mL	0.4190 mL	0.8381 mL	2.0951 mL
	50 mM	0.0670 mL	0.3352 mL	0.6704 mL	1.6761 mL
	60 mM	0.0559 mL	0.2794 mL	0.5587 mL	1.3968 mL
	80 mM	0.0419 mL	0.2095 mL	0.4190 mL	1.0476 mL
	100 mM	0.0335 mL	0.1676 mL	0.3352 mL	0.8381 mL