2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Lintopride hydrochloride

Lintopride hydrochloride, a benzamide, is a potent 5HT-4 antagonist with moderate 5HT-3 antagonist properties. Lintopride hydrochloride increases gastric emptying, stimulates antral and duodenal motility and accelerates intestinal transit in animal. Lintopride hydrochloride significantly increases the lower oesophageal sphincter (LOS) basal tone.

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Lintopride hydrochloride Chemical Structure

Lintopride hydrochloride Chemical Structure

CAS No. : 268548-31-8

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Based on 1 publication(s) in Google Scholar

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Description

Lintopride hydrochloride, a benzamide, is a potent 5HT-4 antagonist with moderate 5HT-3 antagonist properties. Lintopride hydrochloride increases gastric emptying, stimulates antral and duodenal motility and accelerates intestinal transit in animal. Lintopride hydrochloride significantly increases the lower oesophageal sphincter (LOS) basal tone[1].

IC50 & Target[1]

5-HT3 Receptor

 

5-HT4 Receptor

 

Molecular Weight

347.24

Formula

C14H20Cl2N4O2
CAS No.
SMILES

O=C(NCC1=NCCN1CC)C2=CC(Cl)=C(N)C=C2OC.[H]Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Lintopride hydrochloride Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

Lintopride268548-31-85-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorgastric emptyingantralduodenal motilityintestinal transitlower oesophageal sphincterLOSInhibitorinhibitorinhibit

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