1. Vitamin D Related/Nuclear Receptor
  2. Thyroid Hormone Receptor
  3. Liothyronine

Liothyronine  (Synonyms: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3)

Cat. No.: HY-A0070AG
Handling Instructions

Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.

For research use only. We do not sell to patients.

Liothyronine Chemical Structure

Liothyronine Chemical Structure

CAS No. : 6893-02-3

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Description

Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1].

IC50 & Target

TRβ1[1][2]

In Vitro

Liothyronine (GMP) can be used in culture medium for generation of induced pluripotent stem cells from human keratinocytes[1].
Liothyronine (GMP) is necessary in limbal stem cells (LSCs) proliferation and self-renewal[2].
Liothyronine (GMP) (4 nM) promotes cardiac differentiation and maturation of embryonic stem cells[3].
Liothyronine (GMP) (100 Nm, 14 days) promotes electrophysiological maturation of human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

650.97

Formula

C15H12I3NO4

CAS No.
SMILES

OC1=C(I)C=C(OC2=C(I)C=C(C[C@H](N)C(O)=O)C=C2I)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Liothyronine
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HY-A0070AG
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