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J-113397 is a Potent and Selective ORL1 Receptor Antagonist

J-113397 is a potent and selective nonpeptidyl ORL1 receptor antagonist without any agonistic effects on other opioid receptors.
ACY-1083, a Highly Selective HDAC6 Inhibitor, Reverses Chemotherapy-induced Peripheral Neuropathy

ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC50 of 3 nM. ACY-1083 effectively reverses chemotherapy-induced peripheral neuropathy

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