Blogs | MedChemExpress

Targefrin is a Potent EphA2 Antagonist with Antitumor Activity

Targefrin is a potent EphA2-targeting agent, acts as an antagonist, and can be used to research pancreatic cancer.
Reversin 121, a P-glycoprotein Inhibitor, Reverses P-glycoprotein-Mediated Multidrug Resistance

Reversin 121 is a potent P-glycoprotein inhibitor that reverses P-glycoprotein-mediated multidrug resistance.
G12Si-5 is a K-Ras G12S Mutant Covalent Inhibitor

G12Si-5, a potent, selective and reversible covalent inhibitor of the K-Ras G12S, can be used for the research of cancer.
Certepetide is a Tumor-penetrating Enhancer via RGD Motif Interaction with Alphav-integrins

Certepetide is a tumor-penetrating enhancer and has the potential for the research of metastatic pancreatic ductal adenocarcinoma.
Panobinostat is a Potent and Orally Active Non-selective HDAC Inhibitor

Panobinostat, a potent and orally active non-selective HDAC inhibitor, exhibits antineoplastic activities.
FH535 is a Potent Inhibitor of Wnt/β-catenin and PPAR

FH535 is a potent inhibitor of Wnt/β-catenin and PPAR.
PX-12 is an Irreversible Inhibitor of Thioredoxin-1 (Trx-1)

PX-12 is an irreversible inhibitor of Trx-1 and inhibits the growth, migration, and invasion of colorectal cancer cell lines.
IACS-15414 is an Orally Active SHP2 Inhibitor

IACS-15414, a potent and orally active SHP2 inhibitor, exhibits significant anti-tumor efficacy in mouse xenograft model.
β-Lapachone, a Naturally Occurring O-naphthoquinone, is a Topoisomerase I Inhibitor

β-Lapachone, a topoisomerase I inhibitor, induces apoptosis by inhibiting cell cycle progression. β-Lapachone has anti-inflammatory effect.
Troglitazone is an Orally Active PPARγ Agonist

Troglitazone is a potent PPARγ agonist with antitumor activies. Troglitazone has the potential for the research of the pancreatic cancer.

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Blogs (48)