Blogs | MedChemExpress

CGP77675 is an Orally Active Inhibitor of Src Family Kinases

CGP77675 is an orally active and potent inhibitor of Src family kinases with anticancer activity. CGP77675 inhibits Src, EGFR, KDR, v-Abl, and Lck.
AKN-028 is an Orally Active FLT3 Inhibitor

AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor and causes dose-dependent inhibition of FLT3 autophosphorylation.
MYCMI-6 is a Selective Endogenous MYC:MAX Inhibitor

MYCMI-6 is a selective MYC:MAX protein interactions inhibitor, which blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain.
UT-34 is an Orally Active pan-Androgen Receptor Degrader (SARD)

UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with anti-prostate cancer efficacy.
TNO155 is an Orally Active WT SHP2 Inhibitor with Antineoplastic Activity

TNO155 is an allosteric inhibitor of wild-type SHP2. TNO155 has the potential for the study of RTK-dependent malignancies, especially advanced solid tumors.
RBN-2397 is a Selective and Orally Active NAD+ Competitive PARP7 Inhibitor

RBN-2397 is an orally active accross species NAD+ competitive inhibitor of PARP7. RBN-2397 binds to PARP7 and restores interferon (Type I) signaling.
BAY1082439 is an Orally Active and Selective Balanced PI3Kα/β/δ Inhibitor

BAY1082439, an orally bioavailable, selective PI3K inhibitor, inhibits mutated forms of PIK3CA and is effective in treating prostate cancer with PTEN-loss.
OTS514 is a Highly Potent TOPK Inhibitor with Anti-Myeloma Activity

OTS514 is a TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
SNDX-5613 is a Potent and Specific Menin-MLL Inhibitor

SNDX-5613 is a potent, selective, small molecule inhibitor of the Menin-MLL binding interaction for targeted therapy in MLL-rearranged leukemias.
Zotatifin is a Selective and Well-Tolerated eIF4A (Protein Biogenesis) Inhibitor

Zotatifin is a potent and selective eIF4A inhibitor. Zotatifin effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis.

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Blogs (17)