Blogs | MedChemExpress

EEDi-5285 is an Orally Active Embryonic Ectoderm Development (EED) Inhibitor

EEDi-5285 is an exceptionally potent and orally active embryonic ectoderm development (EED) inhibitor with potent anti-cancer activity.
Ilorasertib is an Orally Active ATP-Competitive Multitargeted Kinase Inhibitor

Ilorasertib is a potent inhibitor of Aurora A, B, and C, FLT-3，and the VEGF and PDGF receptor kinases. Activity in acute myeloid leukemia.
SJF620 is a Potent PROTAC BTK Degrader

SJF620 is a potent PROTAC BTK degrader with improved pharmacokinetic properties. Contains a Lenalidomide analog for recruiting CRBN.
CMLD012073, an Amidino-Rocaglates, is a Potent eIF4A Inhibitor

CMLD012073, an Amidino-Rocaglates, is a Potent eIF4A Inhibitor. Amidino- and amino-rocaglates act as potent translation inhibitors and anti-cancer agents.
RapaLink-1, a Third-Generation Bivalent mTOR Inhibitor, Combines Rapamycin with MLN0128

RapaLink-1, a third-generation bivalent mTOR inhibitor, potently blocking cancer-derived, activating mutants of mTOR. It can cross the blood-brain barrier.
AZD-9833 is an Orally Active Estrogen Receptor (ER) Antagonist

AZD-9833 is a potent and orally active ER antagonist. AZD-9833 has the potential for the study of ER+ HER2-advanced breast cancer.
SP-8356 is a Potent and Orally Active CD147 Inhibitor

SP-8356, an orally active CD147inhibitor, exerts anti-breast cancer effects by inhibiting NF-κB signaling. Anti-atherosclerotic effects.
PU02 is an Allosteric Antagonist of 5-HT3 Receptor

PU02, a derivative of 6-MP, is an allosteric antagonist of 5-HT3 receptor. PU02 possesses anti-cancer cativity by inducing aopotosis.
SC99 is an Orally Active and Selective STAT3 Inhibitor

SC99 is an orally active, selective STAT3 inhibitor targeting JAK2-STAT3 pathway. SC99 displays potent anti-myeloma, anti-thrombotic activity.
MPT0G211 is an Orally Active and Selective HDAC6 Inhibitor

MPT0G211, an orally active and selective HDAC6 inhibitor, ameliorates tau phosphorylation, and cognitive deficits in an Alzheimer’s disease model.

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Blogs (18)