Blogs | MedChemExpress

TAS-119 is a Selective and Orally Active Aurora A Inhibitor

TAS-119 is an orally active, selective inhibitor of Aurora kinase A. A clinical candidate for efficacy testing in combination with taxanes.
PF-06843195 is a Selective PI3Kα Inhibitor

PF-06843195 is a selective PI3Kα inhibitor. The Kis of PF-06843195 for PI3Kα and PI3Kδ are less than 0.018 nM and 0.28 nM, respectively.
ML390 is a Potent DHODH Inhibitor

ML390 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor and is an inducer of myeloid differentiation.
Barasertib (AZD1152), a Pro-Drug of Barasertib-hQPA, is a Highly Selective Aurora B Inhibitor

Barasertib (AZD1152) is a pro-drug of Barasertib-hQPA. A selective Aurora B kinase inhibitor. Provides a potential treatment for multiple myeloma.
PR-619 is a Broad-Range DUB Inhibitor

PR-619, a broad-spectrum deubiquitinating enzyme (DUB) inhibitor, induces ER stress and ER-stress related apoptosis.
NSC 33994 is a Selective JAK2 Inhibitor

NSC 33994 (G6) is a selective JAK2 inhibitor. NSC 33994 reduces the levels of pJAK2 in both a dose- and time-dependent manner.
AKI603 is an Aurora Kinase A Inhibitor with Anti-tumor Activity

AKI603 is a potent Aurora kinase inhibitor. AKI603 attenuates breast tumor-initiating cells and overcomes drug resistance.
CXD101 is a Selective and Orally Active Class I HDAC Inhibitor

CXD101 is a selective and orally active class I HDAC inhibitor for advanced cancer.
PF 477736 (PF 00477736) is a Selective and ATP-Competitive Inhibitor of Chk1

PF 477736 (PF 00477736) is a Chk1 inhibitor. Breaching the DNA damage checkpoint. PF-00477736 combines with Gemcitabine to abrogates cell cycle arrest.
Piclidenoson (IB-MECA) is a First-in-Class and Orally Active A3AR Agonist

Piclidenoson (IB-MECA) is an A3 adenosine receptor (A3AR) agonist. Piclidenoson is used for the research of cancer, inflammatory diseases and COVID-19.

Name
Email *

	Sorry, but the email address you supplied was invalid.

Blogs (16)