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Reversine is a potent, ATP-competitive Aurora kinases inhibitor. Reversine is a potential anticancer agent for ALL.
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Telatinib is an orally active inhibitor of VEGFR2, VEGFR3, PDGFα, and c-Kit.
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Nimbolide, a triterpene derived from the leaves and flowers of neem, induces apoptosis through inactivation of NF-κB.
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Ulixertinib is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases.
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WAY 316606 is an inhibitor of the secreted protein sFRP-1.
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Pirarubicin, an anthracycline antibiotics, is a topoisomerase II Inhibitor.
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Bafetinib is an orally active dual Abl/Lyn tyrosine kinase inhibitor. Bafetinib suppresses the growth of Ph+ leukemia cells.
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GNE-149 is an orally bioavailable full antagonist of estrogen receptor α. GNE-149 has potent antitumor activity.
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FH535 is a potent inhibitor of Wnt/β-catenin and PPAR.
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Monastrol, a potent and cell-permeable inhibitor of the mitotic kinesin Eg5, has potential for cancer research.
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