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Panobinostat, a potent and orally active non-selective HDAC inhibitor, exhibits antineoplastic activities.
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AUTAC4 is a Mitochondria-targeting Autophagy-targeting Chimera (AUTAC) and rescues cells with acute mitochondrial injury.
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Henatinib is an orally active small-molecule multikinase inhibitor that has demonstrated broad and potent antitumor activities.
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PSB-SB-487, a Coumarin derivative, is a potent GPR55 antagonist, and is also a partial CB2 receptor agonist.
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Tiragolumab is an immune checkpoint inhibitor binding to TIGIT. Tiragolumab is effective against multiple solid malignancies.
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Pulrodemstat is a potent, selective, reversible and orally active LSD1 inhibitor, with anticancer effects.
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LDN-211904 oxalate is a potent and selective EphB3 inhibitor and combines with cetuximab can overcome cetuximab resistance.
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RKI-1313 is a potent ROCK inhibitor and shows little effect on the phosphorylation levels of ROCK substrates, migration, invasion.
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Toceranib is a selective and orally active inhibitor of RTK and has the potential for the research of canine mast cell tumors.
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AZD7254 is a potent and orally active Smoothened (SMO) inhibitor, against sonic Hh protein (shh), with strong anti-cancer effects.
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