1. GPCR/G Protein Neuronal Signaling
  2. Opioid Receptor
  3. Loxicodegol

Loxicodegol  (Synonyms: Oxycodegol; NKTR-181)

Cat. No.: HY-109064
Handling Instructions

Loxicodegol (Oxycodegol) is a first-in-class, long-acting, orally active, and selective mu-opioid agonist with structural properties that reduce its rate of entry across the blood-brain barrier compared with traditional mu-opioid agonists.

For research use only. We do not sell to patients.

Loxicodegol Chemical Structure

Loxicodegol Chemical Structure

CAS No. : 1211231-76-3

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Description

Loxicodegol (Oxycodegol) is a first-in-class, long-acting, orally active, and selective mu-opioid agonist with structural properties that reduce its rate of entry across the blood-brain barrier compared with traditional mu-opioid agonists[1][2].

Molecular Weight

595.72

Formula

C31H49NO10

CAS No.
SMILES

O[C@@]1(CC[C@H](OCCOCCOCCOCCOCCOCCOC)[C@]2([H])OC3=C4OC)[C@]52C3=C(C=C4)C[C@@]1([H])N(C)CC5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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