1. Metabolic Enzyme/Protease
  2. Phospholipase
  3. Lp-PLA2-IN-6

Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research.

For research use only. We do not sell to patients.

Lp-PLA2-IN-6 Chemical Structure

Lp-PLA2-IN-6 Chemical Structure

CAS No. : 2637485-13-1

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Description

Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research[1].

Molecular Weight

520.45

Formula

C25H21F5N4O3

CAS No.
SMILES

O=C1N=C(C=C2N1CC34N2C(CC4)CCC3)OCC5=CC(F)=C(C(F)=C5)OC6=CC(C(F)(F)F)=NC=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Lp-PLA2-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lp-PLA2-IN-6
Cat. No.:
HY-142774
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