2. Autophagy
  3. LRRK2
  4. LRRK2-IN-3

LRRK2-IN-3 (compoubd 24) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of 2.6 nM in human PBMCs. LRRK2-IN-3 can be used for the research of Parkinson's disease.

For research use only. We do not sell to patients.

LRRK2-IN-3 Chemical Structure

LRRK2-IN-3 Chemical Structure

CAS No. : 2641054-60-4

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LRRK2-IN-3 Related Antibodies

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Description

LRRK2-IN-3 (compoubd 24) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of 2.6 nM in human PBMCs. LRRK2-IN-3 can be used for the research of Parkinson's disease[1].

IC50 & Target

IC50: 2.6 nM (hPBMCs LRRK2)[1]
Molecular Weight

518.99

Formula

C25H29ClF2N6O2
CAS No.
SMILES

FC1([C@@](N2C(C)=C(C=N2)NC3=NC4=C(C=C(C(C5CCN([C@]6([C@H](COC6)O)C)CC5)=C4)Cl)C=N3)([H])C1)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LRRK2-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LRRK2-IN-32641054-60-4LRRK2Leucine-rich repeat kinase 2brain-penetrantParkinson's diseaseInhibitorinhibitorinhibit

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