2. Epigenetics Neuronal Signaling
  3. Histone Demethylase Monoamine Oxidase
  4. LSD1-IN-15

LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor. LSD1-IN-15 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.149, 0.028, and 0.327 μM, respectively. LSD1-IN-15 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 9.9 μM.

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LSD1-IN-15 Chemical Structure

LSD1-IN-15 Chemical Structure

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LSD1-IN-15 Related Antibodies

Top Publications Citing Use of Products

View All Histone Demethylase Isoform Specific Products:

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KDM1/LSD1 KDM2 KDM3 KDM4 KDM5 KDM6

View All Monoamine Oxidase Isoform Specific Products:

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MAO-A MAO-B

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Description

LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor. LSD1-IN-15 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.149, 0.028, and 0.327 μM, respectively. LSD1-IN-15 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 9.9 μM[1].

IC50 & Target

MAO-A

0.028 ± 0. μM (IC50)

MAO-B

0.327 ± 0. μM (IC50)

Molecular Weight

328.41

Formula

C22H20N2O
SMILES

NC1CC1C2=CC=C(C=C2)NC(C3=CC=CC(C4=CC=CC=C4)=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LSD1-IN-15 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LSD1-IN-15Histone DemethylaseMonoamine OxidaseMAOLNCaP cellsU937 cellstranylcypromine (TCP)TCP derivativeprostate cancerLysine-specific demethylase 1 (LSD1)monoamine oxidase (MAO)Inhibitorinhibitorinhibit

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