Lubiprostone (hemiketal) (Synonyms: RU-0211 (hemiketal); SPI-0211 (hemiketal))

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Lubiprostone (hemiketal) (RU-0211 (hemiketal)) is a selective chloride channel 2 (CLCN2) activator. Lubiprostone (hemiketal) is used to treat chronic idiopathic constipation and opioid-induced constipation by activating CLCN2 channels to increase chloride ion secretion in the intestine, thereby increasing intestinal fluid secretion and enhancing intestinal peristalsis. Lubiprostone (hemiketal) can be used in the study of chronic constipation and cancer.

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Lubiprostone (hemiketal) Chemical Structure

CAS No. : 333963-40-9

Size	Price	Stock	Quantity
5 mg	USD 60	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	USD 90	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	USD 180	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	USD 290	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 mg	USD 450	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Other Forms of Lubiprostone (hemiketal):

Lubiprostone In-stock
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Description	Lubiprostone (hemiketal) (RU-0211 (hemiketal)) is a selective chloride channel 2 (CLCN2) activator. Lubiprostone (hemiketal) is used to treat chronic idiopathic constipation and opioid-induced constipation by activating CLCN2 channels to increase chloride ion secretion in the intestine, thereby increasing intestinal fluid secretion and enhancing intestinal peristalsis. Lubiprostone (hemiketal) can be used in the study of chronic constipation and cancer^[1].
Molecular Weight	390.46
Formula	C₂₀H₃₂F₂O₅
CAS No.	333963-40-9
SMILES	CCCCC(F)([C@@]1(O[C@@]2([H])[C@]([C@H](C(C2)=O)CCCCCCC(O)=O)([H])CC1)O)F
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (264 KB) Handling Instructions (2659 KB)
References	[1]. Mitsuda M, et al. Functional analysis and clinical significance of chloride channel 2 expression in esophageal squamous cell carcinoma[J]. Annals of Surgical Oncology, 2021, 28: 5384-5397. [Content Brief]

Lubiprostone (hemiketal) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lubiprostone (hemiketal)333963-40-9RU-0211 (hemiketal) SPI-0211 (hemiketal)Chloride ChannelCl− ChannelsExcitatory regulationconstipationactivatorESCCIFNCLCN2Inhibitorinhibitorinhibit

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Lubiprostone (hemiketal) (Synonyms: RU-0211 (hemiketal); SPI-0211 (hemiketal))

Other Forms of Lubiprostone (hemiketal):

Lubiprostone (hemiketal) Related Antibodies

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•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review