1. Membrane Transporter/Ion Channel
  2. Chloride Channel
  3. Lubiprostone (hemiketal)

Lubiprostone (hemiketal)  (Synonyms: RU-0211 (hemiketal); SPI-0211 (hemiketal))

Cat. No.: HY-B0680
Handling Instructions

Lubiprostone (hemiketal) (RU-0211 (hemiketal)) is a selective chloride channel 2 (CLCN2) activator. Lubiprostone (hemiketal) is used to treat chronic idiopathic constipation and opioid-induced constipation by activating CLCN2 channels to increase chloride ion secretion in the intestine, thereby increasing intestinal fluid secretion and enhancing intestinal peristalsis. Lubiprostone (hemiketal) can be used in the study of chronic constipation and cancer.

For research use only. We do not sell to patients.

Lubiprostone (hemiketal) Chemical Structure

Lubiprostone (hemiketal) Chemical Structure

CAS No. : 333963-40-9

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50 mg USD 290 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 mg USD 450 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
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Description

Lubiprostone (hemiketal) (RU-0211 (hemiketal)) is a selective chloride channel 2 (CLCN2) activator. Lubiprostone (hemiketal) is used to treat chronic idiopathic constipation and opioid-induced constipation by activating CLCN2 channels to increase chloride ion secretion in the intestine, thereby increasing intestinal fluid secretion and enhancing intestinal peristalsis. Lubiprostone (hemiketal) can be used in the study of chronic constipation and cancer[1].

Molecular Weight

390.46

Formula

C20H32F2O5

CAS No.
SMILES

CCCCC(F)([C@@]1(O[C@@]2([H])[C@]([C@H](C(C2)=O)CCCCCCC(O)=O)([H])CC1)O)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lubiprostone (hemiketal)
Cat. No.:
HY-B0680
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