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LY127210 (free base) is a potent vasodilator with antihypertensive effects that reduces pressure in chloralose-anesthetized spontaneously hypertensive rats primarily by direct arteriolar dilation and to a lesser extent by decreasing cardiac output. LY127210 (free base) reduces blood pressure, heart rate and left ventricular end-diastolic pressure in hypertensive rats by reducing vascular resistance.

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LY127210 free base Chemical Structure

LY127210 free base Chemical Structure

CAS No. : 57184-68-6

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Description

LY127210 (free base) is a potent vasodilator with antihypertensive effects that reduces pressure in chloralose-anesthetized spontaneously hypertensive rats primarily by direct arteriolar dilation and to a lesser extent by decreasing cardiac output. LY127210 (free base) reduces blood pressure, heart rate and left ventricular end-diastolic pressure in hypertensive rats by reducing vascular resistance[1].

Molecular Weight

218.25

Formula

C12H14N2O2

CAS No.
SMILES

NC1=NC=CC2=CC(OC)=C(OC)C=C2C1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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LY127210 free base Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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LY127210 free base
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HY-129706
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