2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. LY302148

LY302148 is a receptor ligand for 5-HT1F. Compared to the Emax of 5-HT, LY302148 behaves as a partial agonist for the 5-HT1F receptor. In the [35S]GTPγS binding assay targeting human 5-HT1F receptors, LY302148 exhibits good potency with an EC50 value of 5.23 nM. LY302148 can be used in the research of migraine.

For research use only. We do not sell to patients.

LY302148 Chemical Structure

LY302148 Chemical Structure

CAS No. : 182564-47-2

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LY302148 Related Antibodies

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Description

LY302148 is a receptor ligand for 5-HT1F. Compared to the Emax of 5-HT, LY302148 behaves as a partial agonist for the 5-HT1F receptor. In the [35S]GTPγS binding assay targeting human 5-HT1F receptors, LY302148 exhibits good potency with an EC50 value of 5.23 nM. LY302148 can be used in the research of migraine[1].

Molecular Weight

326.41

Formula

C19H23FN4
CAS No.
SMILES

CN1N=CC(CCN2CCC(C3=CNC4=C3C=C(F)C=C4)CC2)=C1
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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LY302148 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY302148182564-47-2LY 302148LY-3021485-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptormigraineInhibitorinhibitorinhibit

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