m-PEG6-CH2CH2CHO

Cat. No.: HY-W035376: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

m-PEG6-CH2CH2CHO Chemical Structure

CAS No. : 1058691-77-2

Size	Price	Stock
50 mg	USD 115	Ask For Quote & Lead Time
100 mg	USD 150	Ask For Quote & Lead Time
250 mg	USD 180	Ask For Quote & Lead Time
1 g	USD 450	Ask For Quote & Lead Time

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

Non-cleavable Linker

PEGs

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

352.42

Formula

C₁₆H₃₂O₈

CAS No.

1058691-77-2

Appearance

Liquid (Density: 1.1±0.1 g/cm³)

Color

Colorless to light yellow

SMILES

COCCOCCOCCOCCOCCOCCOCCC=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (261 KB) SDS (393 KB)

COA (238 KB) HNMR (111 KB)

Handling Instructions (2659 KB)

References

[1]. Erwin R. Boghaert, et al. Anti-egfr antibody drug conjugates. WO2017214282A1.

m-PEG6-CH2CH2CHO Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

m-PEG6-CH2CH2CHO1058691-77-2ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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