2. Cell Cycle/DNA Damage
  3. Telomerase
  4. Macrocalin B

Macrocalin B is a diterpenoid, which can be isolated from Isodon xerophilus. Macrocalin B inhibits the proliferation of cancer cells K562, HL-60, A549, MKN, CA and HCT with IC50 of 2.81-171 μM. Macrocalin B inhibits the telomerase in K562 with an IC50 in nanomolar level.

For research use only. We do not sell to patients.

Macrocalin B Chemical Structure

Macrocalin B Chemical Structure

CAS No. : 93781-75-0

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Macrocalin B Related Antibodies

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Description

Macrocalin B is a diterpenoid, which can be isolated from Isodon xerophilus. Macrocalin B inhibits the proliferation of cancer cells K562, HL-60, A549, MKN, CA and HCT with IC50 of 2.81-171 μM. Macrocalin B inhibits the telomerase in K562 with an IC50 in nanomolar level[1].

Molecular Weight

362.42

Formula

C20H26O6
CAS No.
SMILES

O[C@@]12[C@]34[C@]5([H])[C@]6([C@](C(C)(CCC6)C)([H])[C@@H]2O)[C@](O[C@@]3([H])[C@](C[C@@H]5O)([H])C(C4=O)=C)([H])O1
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Macrocalin B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Macrocalin B93781-75-0TelomeraseK562HL-60A549MKNCAHCTInhibitorinhibitorinhibit

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