Mal-Cyclohexyl-PEG3-Biotin

Cat. No.: HY-W800679: FAQs
Data Sheet Handling Instructions Technical Support

Mal-Cyclohexyl-PEG3-Biotin is a PEG linker containing a maleimide moiety and a biotin group. Maleimides react specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The biotinylation can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.

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Mal-Cyclohexyl-PEG3-Biotin Chemical Structure

CAS No. : 2639395-45-0

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Description	Mal-Cyclohexyl-PEG3-Biotin is a PEG linker containing a maleimide moiety and a biotin group. Maleimides react specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The biotinylation can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.
Molecular Weight	637.79
Formula	C₃₀H₄₇N₅O₈S
CAS No.	2639395-45-0
SMILES	O=C(C1CCC(CC1)CN2C(C=CC2=O)=O)NCCOCCOCCOCCNC(CCCC[C@H]3[C@]4([H])[C@](NC(N4)=O)([H])CS3)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (237 KB) Handling Instructions (2659 KB)