Mal-GGG-Bal-NHS ester

Name: Mal-GGG-Bal-NHS ester
Brand: MedChemExpress
SKU: HY-160408
Rating: 4.5 (1 reviews)

Cat. No.: HY-160408 Purity: 97.60%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Mal-GGG-Bal-NHS ester Chemical Structure

CAS No. : 1193111-65-7

Size	Price	Stock	Quantity
5 mg	USD 700	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
Customer Review

Description

Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

Molecular Weight

522.47

Formula

C₂₁H₂₆N₆O₁₀

CAS No.

1193111-65-7

Appearance

Solid

Color

White to off-white

SMILES

O=C(CCNC(CNC(CNC(CNC(CCCN1C(C=CC1=O)=O)=O)=O)=O)=O)ON2C(CCC2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (95.70 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9140 mL	9.5699 mL	19.1399 mL
5 mM	0.3828 mL	1.9140 mL	3.8280 mL
10 mM	0.1914 mL	0.9570 mL	1.9140 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 97.60%

Select Batch:

Data Sheet (265 KB) SDS (251 KB)

COA (245 KB) HNMR (433 KB) LCMS (122 KB)

Handling Instructions (2659 KB)

References

[1]. Beck A, et, al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.9140 mL	9.5699 mL	19.1399 mL	47.8496 mL
	5 mM	0.3828 mL	1.9140 mL	3.8280 mL	9.5699 mL
	10 mM	0.1914 mL	0.9570 mL	1.9140 mL	4.7850 mL
	15 mM	0.1276 mL	0.6380 mL	1.2760 mL	3.1900 mL
	20 mM	0.0957 mL	0.4785 mL	0.9570 mL	2.3925 mL
	25 mM	0.0766 mL	0.3828 mL	0.7656 mL	1.9140 mL
	30 mM	0.0638 mL	0.3190 mL	0.6380 mL	1.5950 mL
	40 mM	0.0478 mL	0.2392 mL	0.4785 mL	1.1962 mL
	50 mM	0.0383 mL	0.1914 mL	0.3828 mL	0.9570 mL
	60 mM	0.0319 mL	0.1595 mL	0.3190 mL	0.7975 mL
	80 mM	0.0239 mL	0.1196 mL	0.2392 mL	0.5981 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.