2. PROTAC
  3. PROTAC Linkers
  4. Mal-PEG5-NHS ester

Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Mal-PEG5-NHS ester Chemical Structure

Mal-PEG5-NHS ester Chemical Structure

CAS No. : 1807537-42-3

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Based on 1 publication(s) in Google Scholar

Mal-PEG5-NHS ester Related Antibodies

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Description

Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target

PEGs

 

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mal-PEG5-NHS ester Related Antibodies
Molecular Weight

486.47

Formula

C21H30N2O11
CAS No.
Appearance

Liquid (Density: 1.34±0.1 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCN2C(C=CC2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
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Mal-PEG5-NHS ester Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mal-PEG5-NHS ester1807537-42-3PROTAC LinkersPEGAlkyl/etherlinkercancerprotacInhibitorinhibitorinhibit

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Mal-PEG5-NHS ester
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HY-126888
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