1. PROTAC
  2. PROTAC Linkers
  3. Mal-PEG8-NHS ester

Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Mal-PEG8-NHS ester Chemical Structure

Mal-PEG8-NHS ester Chemical Structure

CAS No. : 2055033-05-9

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50 mg USD 50 In-stock
100 mg USD 80 In-stock
250 mg USD 155 In-stock
1 g USD 425 In-stock
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Description

Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

618.63

Formula

C27H42N2O14

CAS No.
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN2C(C=CC2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 98.44%

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Mal-PEG8-NHS ester Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mal-PEG8-NHS ester
Cat. No.:
HY-126887
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