2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Maleimide-PEG8-Val-Ala-PAB

Maleimide-PEG8-Val-Ala-PAB is an ADC linker composed of the cleavable Val-Ala-PAB (HY-125933) linker and the probe molecule Maleimide (HY-W007324). Maleimide-PEG8-Val-Ala-PAB can be used to connect Cetuximab (HY-P9905) monoclonal antibody and CDK inhibitor SNS-032 (HY-10008) to synthesize antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Maleimide-PEG8-Val-Ala-PAB Chemical Structure

Maleimide-PEG8-Val-Ala-PAB Chemical Structure

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Maleimide-PEG8-Val-Ala-PAB Related Antibodies

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Description

Maleimide-PEG8-Val-Ala-PAB is an ADC linker composed of the cleavable Val-Ala-PAB (HY-125933) linker and the probe molecule Maleimide (HY-W007324). Maleimide-PEG8-Val-Ala-PAB can be used to connect Cetuximab (HY-P9905) monoclonal antibody and CDK inhibitor SNS-032 (HY-10008) to synthesize antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable ADC Linker[1]
Molecular Weight

867.98

Formula

C41H65N5O15
SMILES

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@H](C(N[C@@H](C)C(NC1=CC=C(CO)C=C1)=O)=O)C(C)C)=O)CCN2C(C=CC2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Maleimide-PEG8-Val-Ala-PAB Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Maleimide-PEG8-Val-Ala-PABADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
Maleimide-PEG8-Val-Ala-PAB
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HY-163675
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