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  4. MBP Ac1-9 (4Y)

MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis.

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MBP Ac1-9 (4Y) Chemical Structure

MBP Ac1-9 (4Y) Chemical Structure

CAS No. : 167278-49-1

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Description

MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis[1].

Molecular Weight

1134.20

Formula

C47H75N17O16

CAS No.
Sequence

Ac-Ala-Ser-Gln-Tyr-Arg-Pro-Ser-Gln-Arg

Sequence Shortening

Ac-ASQYRPSQR

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MBP Ac1-9 (4Y)
Cat. No.:
HY-P10525
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